%0 Journal Article
%T Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses
%A Tang Sai-Wen
%A Ducroux Aurelie
%A Jeang Kuan-Teh
%A Neuveut Christine
%J Journal of Biomedical Science
%D 2012
%I BioMed Central
%R 10.1186/1423-0127-19-92
%X Autophagy is a protein degradative process important for normal cellular metabolism. It is apparently used also by cells to eliminate invading pathogens. Interestingly, many pathogens have learned to subvert the cell¡¯s autophagic process. Here, we review the interactions between viruses and cells in regards to cellular autophagy. Using findings from hepatitis B virus and human retroviruses, HIV-1 and HTLV-1, we discuss mechanisms used by viruses to usurp cellular autophagy in ways that benefit viral replication.
%U http://www.jbiomedsci.com/content/19/1/92