%0 Journal Article
%T The Comparison of Salivary IgA and IgE Levels in Children with Breast- and Formula- Feeding During Infancy Period
%A A. Jafarzadeh
%A GH. Hassanshahi
%A M. Kazemi-Arababadi
%A A. Mostafaee
%J Dental Research Journal
%D 2007
%I Isfahan University of Medical Sciences
%X Introduction: Oral local immune factors may play a protective role against oral diseases and defend against microbial agents. Salivary immunoglobulin A (IgA) is a major factor for the local host defence against caries and periodontal disease. The aims of this study were to determine the concentrations of salivary IgA and IgE levels in breast-fed and formula-fed children in infancy period.Methods and Materials: Totally, 80 healthy 5 years old children were included in the study. According to type of feeding in infancy period, the children divided into two groups: 50 breast-fed and 30 formula-fed. One milliliter of saliva was collected from each participant, centrifuged, and stored at -70 )C. The salivary IgA and IgE concentrations were measured, using ELISA technique.Results: In breast-fed children, the salivary IgA level (39.6 mg/l ¡À 17.3) was significantly higher than that in formula-fed children (26.9 mg/l ¡À 14) (P=0.0001). However, the salivary IgE level was significantly lower in breast-fed children, comparing with formula fed ones (5.01 IU/ml ¡À 19.70 vs. 11.74 IU/ml ¡À 39.40) (P=0.047).Discussion: These results suggest that breast feeding enhances salivary IgA level in the early period of life which may contribute in oral cavity immunity. Higher salivary IgE level observed in formula-fed subjects may have a potential role in development of allergic or inflammatory reactions.
%K Breast Feeding
%K Formula Feeding
%K Saliva
%K IgA
%K IgE
%K Children
%U http://journals.mui.ac.ir/drj/article/view/1544/623