%0 Journal Article
%T Biomechanical evaluation of predictive parameters of progression in adolescent isthmic spondylolisthesis: a computer modeling and simulation study
%A Amandine Sevrain
%A Carl-Eric Aubin
%A Hicham Gharbi
%A Xiaoyu Wang
%A Hubert Labelle
%J Scoliosis
%D 2012
%I BioMed Central
%R 10.1186/1748-7161-7-2
%X A finite element model of a low-grade L5-S1 spondylolisthesis was constructed, including the morphology of the spine, pelvis and rib cage based on measurements from biplanar radiographs of a patient. Variations provided on this model aimed to study the effects on low grade spondylolisthesis as well as reproduce high grade spondylolisthesis. Normal and shear stresses at the lumbosacral junction were analyzed under various pelvic incidences, sacral slopes and slip percentages. Their influence on progression risk was statistically analyzed using a one-way analysis of variance.Stresses were mainly concentrated on the growth plate of S1, on the intervertebral disc of L5-S1, and ahead the sacral dome for low grade spondylolisthesis. For high grade spondylolisthesis, more important compression and shear stresses were seen in the anterior part of the growth plate and disc as compared to the lateral and posterior areas. Stress magnitudes over this area increased with slip percentage, sacral slope and pelvic incidence. Strong correlations were found between pelvic incidence and the resulting compression and shear stresses in the growth plate and intervertebral disc at the L5-S1 junction.Progression of the slippage is mostly affected by a movement and an increase of stresses at the lumbosacral junction in accordance with spino-pelvic parameters. The statistical results provide evidence that pelvic incidence is a predictive parameter to determine progression in isthmic spondylolisthesis.Spondylolisthesis is a spinal condition characterized by a posteroanterior slippage of one vertebra over the vertebra immediately below [1-4]. The biomechanics of its occurrence and progression is yet to be fully studied. The knowledge on its biomechanics is essential for its clinical prediction and the improvement of its treatment. Spondylolisthesis was thought to be closely related to spondylolysis which is a unilateral or bilateral pars defect of a vertebra that affects 5-6% of the population
%K Isthmic spondylolisthesis
%K finite element model
%K pelvic incidence
%K biomechanical model
%U http://www.scoliosisjournal.com/content/7/1/2