%0 Journal Article
%T Dosimetric Improvements in Balloon Based Brachytherapy Using the Contura  Multi-Lumen Balloon (MLB) Catheter to Deliver Accelerated Partial Breast Irradiation
%A Frank A Vicini
%A Arthur Douglas
%A Thomas Julian
%A Maureen Lyden
%J Journal of Contemporary Brachytherapy
%D 2010
%I Termedia Publishing House
%X Purpose: Preliminary dosimetric findings in patients managed with the Contura  Multi-Lumen Balloon (MLB) breast brachytherapy catheter to deliver accelerated partial breast irradiation (APBI) on a multi-institutional phase IV registry trial were reviewed. Material and methods: CT-based 3D planning with dose optimization was performed for all patients. For the study, new ideal dosimetric goals were developed: 1) ¡Ý 95% of the prescribed dose (PD) covering ¡Ý 90% of the target volume (TV), 2) a maximum skin dose ¡Ü 125% of the PD, 3) maximum rib dose ¡Ü 145% of the PD, and 4) the V150 ¡Ü 50 cc and V200 ¡Ü 10 cc. The frequency of concurrently achieving these dosimetric goals using the Contura  MLB was investigated.Results: 194 cases were evaluable. Employing the MLB, all ideal dosimetric criteria were achieved in 76% of cases.Evaluating dosimetric criteria separately, 90% and 89% of cases met the new ideal skin and rib dose criteria, respectively. In 96%, ideal TV coverage goals were achieved and in 96%, dose homogeneity criteria (V150 and V200) were met. For skin spacing ¡Ý 5-7 mm, the median skin dose was 121% of the PD and when < 5 mm, the median skin dose was 124.4%. For rib distancees < 5 mm, the median rib dose was reduced to 136.4% of the PD. For skin spacing < 7 mm and distance to rib < 5 mm, the median skin and rib doses were concurrently limited to 121% and 142.8% of thePD, respectively. Conclusions: The Contura  MLB catheter provides potential improvements in dosimetric capabilities (i.e., reduced skin and rib doses and improved TV coverage) in many clinical scenarios.
%K breast conserving therapy
%K balloon brachytherapy
%K Contura .
%U http://www.termedia.pl/Clinical-Investigations-Dosimetric-Improvements-in-Balloon-Based-Brachytherapy-Using-the-Contura-reg-Multi-Lumen-Balloon-MLB-Catheter-to-Deliver-Accelerated-Partial-Breast-Irradiation,54,14479,1,1.html