%0 Journal Article
%T Comparison of 3,000 and 5,000 IU aXa/day certoparin in the prevention of deep-vein thrombosis after total hip replacement
%A Peter Bramlage
%A Hans Christoph Michaelis
%A Nima Melzer
%J Thrombosis Journal
%D 2012
%I BioMed Central
%R 10.1186/1477-9560-10-10
%X Mean age was 71£¿¡À£¿10£¿years with a higher prevalence of previous DVT (8vs.4%) and pulmonary embolism (PE) (4vs.1%) in the high dose group. Mean duration of surgery was 82£¿¡À£¿32 and 85£¿¡À£¿36 min. DVT was detected in 28 (11.1%) of the low dose and 35 (14.1%) of the high dose group (p£¿=£¿n.s.). Combined distal-proximal DVT was observed in 5 (2%) and 4 (1.6%) patients respectively. No difference in bleeding events was found.This trial confirms prior data showing that the conventional dosage of 3,000£¿IU aXa is effective and safe for the prevention of venous thromboembolic events after hip replacement surgery.
%U http://www.thrombosisjournal.com/content/10/1/10/abstract