%0 Journal Article
%T A complete response to S-1 plus cis-diamminedichloroplatinum in advanced-stage esophageal and gastric adenocarcinoma: a case report
%A Yoritaka Matsuno
%A Mitsugu Kochi
%A Masashi Fujii
%A Noriaki Kanamori
%A Teruo Kaiga
%A Yoshiaki Mihara
%A Tomoya Funada
%A Akiyuki Miyazaki
%A Tadatoshi Takayama
%J World Journal of Surgical Oncology
%D 2012
%I BioMed Central
%R 10.1186/1477-7819-10-133
%X The patient was a 74-year-old man referred to our hospital complaining of dysphagia. Gastrointestinal endoscopy was performed and advanced-stage SDP esophageal and gastric adenocarcinoma diagnosed. Computed tomography revealed multiple regional lymph node metastases in the mediastinum. Neoadjuvant chemotherapy with S-1 and CDDP for advanced esophageal and gastric cancer was planned. An endoscopy following two courses of chemotherapy revealed that the esophageal cancer had been replaced with a normal mucosal lesion and the gastric tumor with a scar lesion; the results of biopsies of both were negative for cancer. Computed tomography revealed that the multiple lymph node metastases had disappeared. We diagnosed a complete response to S-1 and CDDP in advanced-stage SDP esophageal and gastric cancer. The patient is still alive with no signs of recurrence 22£¿months after the disappearance of the original tumor and metastatic lesions without surgical treatment.These results suggest that complete remission from advanced-stage esophageal and gastric cancer can be obtained with chemotherapy with S-1 plus CDDP.
%K Chemotherapy
%K Complete response
%K Esophageal cancer
%K Gastric cancer
%U http://www.wjso.com/content/10/1/133/abstract