%0 Journal Article
%T Diffusion-weighted imaging and FDG PET/CT: predicting the prognoses with apparent diffusion coefficient values and maximum standardized uptake values in patients with invasive ductal carcinoma
%A Bo Bae Choi
%A Sung Hun Kim
%A Bong Joo Kang
%A Ji Hye Lee
%A Byung Joo Song
%A Seung Hee Jeong
%A Hyeon Woo Yim
%J World Journal of Surgical Oncology
%D 2012
%I BioMed Central
%R 10.1186/1477-7819-10-126
%X Patients with pathologically confirmed IDC were recruited. There were 118 patients who underwent MRI, including DWI, FDG PET/CT, and immunohistochemical staining of the surgical specimen. Histologic analysis was done on tumor size, lymph node metastasis, expression of estrogen receptors (ER), progesterone receptors (PR), human epidermal growth factor receptor 2 (HER2), Ki-67, and epidermal growth factor receptors (EGFR). The relationship among ADC values, SUVmax and prognostic factors were evaluated.There was significant association between the ADC value and ER-positive and HER2-negative expression. Significant associations were noted between SUVmax and tumor size, lymph node metastasis, histologic grade, ER and PR expression, EGFR and Ki-67. However, there was no significant correlation between the ADC value and SUVmax.Even though there was no correlation between ADC and SUVmax, both indexes are useful for predicting the prognosis of IDC.
%K Invasive ductal carcinoma
%K breast
%K magnetic resonance imaging
%K diffusion magnetic resonance imaging
%K positron emission tomography
%U http://www.wjso.com/content/10/1/126/abstract