%0 Journal Article
%T Bone loss in inflammatory Bowel disease: our multicentric study
%A Alessandro Geraci
%A Giovanni Tomasello
%A Provvidenza Damiani
%A Guido Mazzoccato
%J Endocrinology Studies
%D 2011
%I PAGEPress Publications
%R 10.4081/es.2011.e3
%X Patients with inflammatory bowel disease are at increased risk of developing disorder in bone and mineral metabolism The study was aimed to determine if inflammatory bowel disease (IBD) is a risk factor for osteoporosis in 103 adult patients. We included 103 IBD patients, 67 patients with Crohn¡¯s disease (CD) and 36 with ulcerative colitis (UC). Bone mineral density was measured by dual-energy X-ray absorptiometry. We used T score to express bone loss (osteopenia: -2.5 SD <-1 SD, osteoporosis: T <-2.5 SD). Plain x-rays were examined to search for vertebral compression or spontaneous fractures before DEXA. Among the 103 patients, 47.7% exhibited osteopenia of the femoral neck and 62.3% of the lumbar spine, with no significant difference between CD and UC. The prevalence of osteoporosis of the lumbar spine was significantly higher in CD patients (41.2% versus 8.7%). Osteoporosis is frequent in IBD patients, especially in CD patients. Female gender, malnutrition (body mass index <20 kg/m2), disease course (>2 years) and active disease would be risk factors of bone mineral loss in IBD.
%U http://www.pagepress.org/journals/index.php/es/article/view/2112