%0 Journal Article
%T SYNTHESIS AND BIOLOGICAL EVALUATION OF SOME N-METHYLATED DERIVATIVES OF THIAZOLYLAMINO ACIDS AND PEPTIDES
%A M. Himaja
%A Gupta Nitesh
%A D. Munirajasekhar
%A Karigar Asif
%J Journal of Pharmaceutical and Scientific Innovation
%D 2012
%I Moksha Publishing House
%X A series of substituted thiazole containing N-methylated amino acids and peptides were synthesized by solution phase technique and were subjected to evaluation of biological activities. In this project 2-amino-4-phenylthiazole is synthesized and then coupled with protected amino acid. In case of dipeptide, protected amino acids are condensed together to get dipeptide using DIPC ( di-isopropylcarbodiimide) and then dipeptide is condensed to 2-amino-4-phenyl thiazole using coupling agent to get the final compound. Synthesized compounds are characterized and anthelmintic and insecticidal activity studies were performed.
%K Solution Phase Technique
%K Thiazole
%K Linear Peptides
%K Anthelmintic
%K Insecticidal.
%U http://jpsionline.com/admin/php/uploads/42_pdf.pdf