%0 Journal Article %T Hypothalamic-pituitary-gonadal axis responses of the male rats to short and long time alternative magnetic fields (50 Hz) exposure %A akram ahangarpour %A Hadi Fathi-Moghaddam %A Mohammad Javad Tahmasebi Birgani %A Hajieh Shahbazian %J Journal of Research in Medical Sciences %D 2009 %I Isfahan University of Medical Sciences %X BACKGROUND: Electromagnetic fields are associated with production, transmission and use of electricity. In this tudy we have investigated the effects of short and long time alternative magnetic fields' (AMF, 50 Hz) exposure on the secretion of hypothalamic-pituitary-gonadal axis in the male rats. METHODS: Forty eight Wistar male rats, same range of age and weight were divided into four groups and each group contained 12 rats. After one-week adaptation each roup were exposed to AMF (0, 25, 50 and 100 4T espectively) for 17 days, 5 hours a day. In the second protocol the time of exposure extended to 34 days. After experiments rats' blood serums were removed from their blood samples and kept frozen for usage. The results were analyzed by one way- ANOVA statistical method (p < 0.05). RESULTS: Chronic exposures (5h/day for 34 days) to AMFs had no effect on serum's testosterone and LH. But, AMF t 100 4T induced an increase of serum's FSH level in omparison with 25 ¦ĚT, 50 4T and control groups. In contrast, subchronic AMFs (5 h/day for 17 days) induced a decrease of serum's testosterone in control group in omparison with 25, 50 and 100 4T groups. But these AMFs had no effect on serum's LH and FSH levels. CONCLUSIONS: Increased level of FSH suggests damage to the seminiferous tubules. Our results suggest that AMFs probably causes dysfunction in gonadal axis at the hypothalamic-pituitary level in male rats in different protocols. KEYWORDS: Sex Hormones, Male Rats, Magnetic Field. %K Sex hormones %K male rats %K magnetic Field %U http://journals.mui.ac.ir/jrms/article/view/2329