%0 Journal Article
%T TRANSITION METAL COMPLEXES OF SALICYLALDEHYDE NICOTINOYL HYDRAZONE (SANH) SYNTHESIS, CHARACTERIASATION AND ANTIBACTERIAL ACTIVITY
%A Borhade Shobha
%J Journal of Pharmaceutical and Scientific Innovation
%D 2012
%I Moksha Publishing House
%X Salicylaldehyde nicotinoyl hydrazone ( SANH ) has been synthesized. Complexes of Salicylaldehyde nicotinoyl hydrazone with transition metals, Fe (II) & Cu (II) have been synthesized in ethanol medium. The formation of the complexes are endothermic processes. The ligand was characterized by melting point, elemental analysis, absorption spectra, NMR - 1 H prediction and antimicrobial activity while the complexes were characterized by melting point,absorption spectra. A simple & sensitive spectrophotometric method was developed for transition metal complexes of SANH. The optimum condition for complete colour development have been established. The stability constant, dissociation constant & change in free energy of Fe (II) & Cu (II) complexes with SANH are determined. Composition of the metal & ligand has been determined by JobĄ¯s variation & mole ratio method indicate that the M:L is 2:1. Tolerance limit of diverse ions in the determination of Fe (II) & Cu (II) with Salicylaldehyde nicotinoyl hydrazone are investigated.
%K Salicylaldehyde nicotinoyl hydrazone
%K Fe (II)
%K Cu (II)
%K Spectrophotometry
%K Antimicrobial activity.
%U http://jpsionline.com/admin/php/uploads/57_pdf.pdf