%0 Journal Article
%T 普洱茶调节apoE基因敲除小鼠血脂水平的研究<br>The Regulation of Pu-erh Tea on
Blood Lipids in apoE-Gene Knocked Mice
%A 江新凤
%A 邵苑芳
%A 刘彩霞
%A 程春华
%A 杨继红
%J Asian Case Reports in Genetics
%P 1-5
%@ 2328-0425
%D 2013
%I Hans Publishing
%R 10.12677/ACRG.2013.11001
%X <div style=\"text-align:justify;\">
	<span style=\"line-height:1.5;\">为了验证普洱茶对</span><span style=\"line-height:1.5;\">apoE</span><span style=\"line-height:1.5;\">基因敲除小鼠动脉粥样硬化的作用；本研究选取了</span><span style=\"line-height:1.5;\">40</span><span style=\"line-height:1.5;\">只</span><span style=\"line-height:1.5;\">4</span><span style=\"line-height:1.5;\">周龄雄性</span><span style=\"line-height:1.5;\">apoE</span><span style=\"line-height:1.5;\">基因敲除小鼠，按照体重随机分成降脂药组、模型组、生茶组、熟茶组</span><span style=\"line-height:1.5;\">4</span><span style=\"line-height:1.5;\">组外加</span><span style=\"line-height:1.5;\">10</span><span style=\"line-height:1.5;\">只正常对照组。用普洱茶汤进行干预性试验</span><span style=\"line-height:1.5;\">90</span><span style=\"line-height:1.5;\">天后，空腹</span><span style=\"line-height:1.5;\">12</span><span style=\"line-height:1.5;\">小时，摘眼球采血，采用全自动生化仪测血清中的总胆固醇</span><span style=\"line-height:1.5;\">(TC)</span><span style=\"line-height:1.5;\">、甘油三酯</span><span style=\"line-height:1.5;\">(TG)</span><span style=\"line-height:1.5;\">、低密度脂蛋白</span><span style=\"line-height:1.5;\">(LDL-C)</span><span style=\"line-height:1.5;\">、高密度脂蛋白</span><span style=\"line-height:1.5;\">(HDL-C)</span><span style=\"line-height:1.5;\">等血脂指标；试验结果显示：普洱茶</span><span style=\"line-height:1.5;\">(</span><span style=\"line-height:1.5;\">生、熟</span><span style=\"line-height:1.5;\">)</span><span style=\"line-height:1.5;\">均可显著控制小鼠体重增长</span><span style=\"line-height:1.5;\">(</span><span style=\"line-height:1.5;\">P</span><span style=\"line-height:1.5;\"> &lt; </span><span style=\"line-height:1.5;\">0.05</span><span style=\"line-height:1.5;\">)</span><span style=\"line-height:1.5;\">；普洱生茶可显著降低小鼠血清中</span><span style=\"line-height:1.5;\">TG</span><span style=\"line-height:1.5;\">、</span><span style=\"line-height:1.5;\">LDL-C</span><span style=\"line-height:1.5;\">的含量，升高</span><span style=\"line-height:1.5;\">HDL-C</span><span style=\"line-height:1.5;\">的含量</span><span style=\"line-height:1.5;\">(</span><span style=\"line-height:1.5;\">P &lt; 0.05</span><span style=\"line-height:1.5;\">)</span><span style=\"line-height:1.5;\">，可显著降低</span><span style=\"line-height:1.5;\">AI</span><span style=\"line-height:1.5;\">系数；因此可判定，普洱茶对</span><span style=\"line-height:1.5;\">apoE</span><span style=\"line-height:1.5;\">基因敲除小鼠的抗动脉粥样硬化有一定的调节作用。</span>
</div>
<div style=\"text-align:justify;\">
	<span style=\"line-height:1.5;\">This study aimed to investigate the effects of Pu-erh tea on blood lipids in apoE-knockout mice. So we selected 4-week-old male apoE-gene knocked mice, and they were randomly divided into four groups:
%K 普洱茶；动脉粥样硬化；apoE基因敲除小鼠<br>Pu-erh Tea
%K Atherosclerosis
%K The Mice of apoE-Gene Knocked
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=9495