%0 Journal Article
%T Synthesis of novel 2-propenoyl amides, esters, heterocyclic compounds and their screening as antifungal and antibacterial agents
%A Ahmed El-Ziaty
%A Abdelaal Abdalh
%A Ashraf Hamed
%A Sayed Shiba
%J European Journal of Chemistry
%D 2012
%I 
%R 10.5155/eurjchem.3.1.65-70.518
%X Compound, 2-cyano-3-(2¨@,4¨@-dichlorophenyl)-2-prpoenoyl chloride, 3, was reacted with nitrogen, sulfur, and oxygen nucleophilic reagents to give new 2-propenoyl amide and ester derivatives. Some of these derivatives were cyclized under the reaction conditions and/or with POCl3 or Ac2O to give new derivatives of heterocyclic systems. Some of these compounds were tested as antibacterial and antifungal agents.
%K Oxadiazole
%K Benzoxazinone
%K Pyridopyrimidine
%K 2-Propenoyl amide
%K 2-Propenoyl chloride
%K Antibacterial activities
%U http://www.eurjchem.com/index.php/eurjchem/article/view/518