%0 Journal Article
%T Application of sulfonic acid functionalized nanoporous silica (SBA-Pr-SO3H) in the solvent free synthesis of (E)-arylidene-1,3-dihydroindole-2-ones
%A Parisa Gholamzadeh
%A Ghodsi Mohammadi Ziarani
%A Alireza Badiei
%A Zohreh Bahrami
%J European Journal of Chemistry
%D 2012
%I 
%R 10.5155/eurjchem.3.3.279-282.630
%X An efficient and green condensation reaction is developed for the synthesis of (E)-arylidene-1,3-dihydroindole-2-ones; (1), using heterogeneous nanoporous acid catalyst of SBA-Pr-SO3H with pore size, 6 nm in solvent free condition. Arylidene-1,3-dihydroindole-2-ones have many pharmaceutical properties such as Tyrosin kinase inhibiton. This method has the advantages of short reaction time, isolation ease of the products, excellent yields and recyclable catalyst.
%K Oxindole
%K SBA-Pr-SO3H
%K Green synthesis
%K Solvent free reaction
%K Tyrosin kinase inhibitor
%K Arylidene-1
%K 3-dihydroindole-2-ones
%U http://www.eurjchem.com/index.php/eurjchem/article/view/630