%0 Journal Article
%T An¨¢lise da evolu  o de culturas neurais
%A Su¨¦len Moreira Marques
%A Mauro Guilherme Guzo
%A Ricardo de Camargos Lopes
%A Ariadne de Almeida Branco Oliveira
%J Exacta
%D 2012
%I Universidade Nove de Julho
%X This paper analyses the electrical activity recorded in an experiment involving the maturation of dissociated embryonic hippocampal cultures, using Multielectrode Array (MEA) devices, starting from the moment of the culture's placement in the device until its death, a period of 0 to 88 days in vitro (DIV). Classical "spike" analysis is applied to three different cultures, showing the progression of  spikes  and "bursts". Particular attention is devoted to the last step associated with cellular death, as an unexpected rise in electrical activity amplitude is observed.
%U http://www.redalyc.org/articulo.oa?id=81023342013