%0 Journal Article %T The Cost of Cancer Care: Navigation Challenges to Participation in Phase I Clinical Trials %A Wanda Strange %A Shannon Cagnina %A Cynthia Bedell %A John J. Nemunaitis %J Cancer and Clinical Oncology %D 2012 %I %R 10.5539/cco.v1n2p86 %X Phase I trial participation for advanced cancer patients is often a ¡°last resort¡± in an attempt to control progressive disease. It is also a necessary component mandated by our investigative community and FDA to characterize safety and mechanism via dose and schedule modulation of experimental therapeutics. Participation in phase I studies is difficult without support. The purpose of this assessment is to provide mechanisms of support established by nurse navigation to facilitate phase I trial patient participation. %U http://www.ccsenet.org/journal/index.php/cco/article/view/19667