%0 Journal Article %T The effectiveness of cream with Centella Asiatica and Pinus Sylvestris to treat scars and burns. Clinical Trial %A Edelisa Moredo Romo %A Fernanda Pastrana Fundora %A Cesar Ram¨ªrez Albajes %A Lissette Esteris L¨®pez %J Clinical Dermatology %D 2012 %I %X Background: Scars and burns are ever increasing complaints among children that turn to dermatologists to find a solution for the permanent, anaesthetic marks that they usually leave. Aim of the study: Determine how effective Cicatrix cream (Catalysis laboratories Madrid, Spain) is to treat post-operative scars and second degree burns, and to provide patients with an alternative therapy that provides aesthetic benefits in a short period of time and has minimum adverse reactions. Material and methods: A Phase II, open-label, controlled clinical trial was organised, that included 100 patients of both genders, aged between 0 and 18 years old, who had been diagnosed as having postoperative scars and burns at the Dermatology Service at the Pediatric Hospital Juan Manuel M¨¢rquez. Scars and burns were evaluated (colour, size) several times during the clinical trial. The sample was stratified according to the type of lesion and the gender and age groups in the stratus were homogenous. The Cicatrix cream was applied on the lesion twice a day for eight weeks. Results: 57.1% of the burns completely disappeared after 8 weeks of the treatment and 46.7% of the scars got smaller by more than 50%. There was more than 50% improvement in colour for 95.2% of the burns and 72% of the scars. 98.7% of the patients with scars and 100% of the patients with burns responded well to the treatment. There were no adverse reactions. Conclusions: Cicatrix is an excellent therapeutic alternative to treat these problems. %U http://cornetis.pl/pliki/DK/2012/3/DK_2012_3_105.pdf