%0 Journal Article %T Commonality Between Diabetes and Alzheimer¡¯s Disease and A New Strategy for the Therapy %A Li Lin %J Clinical Medicine : Pathology %D 2008 %I %X A surprising common pathological processes is found between Alzheimer¡¯s disease (AD) and type 2 diabetes mellitus (T2DM)[1]. AD and T2DM share some common pathological processes: Amyloid ¦Â (A¦Â), ¦Ó hyperphosphoralation, insulin abnormality. Disturbance in insulin signalling is not only involved in blood glucose level but also in numerous degenerative processes. Glucagon-like peptide 1 (GLP-1) has attracted substantial attention for its advantage in treating T2DM. GLP-1 can reduce A¦Â levels in brain. All these encourage us in a medical hypothesis: that is, that GLP-1 is a promising agent in the therapy of AD. %K Glucagon-like peptide 1 %K Diabetes %K Alzheimer¡¯s disease %U http://la-press.com/article.php?article_id=928