%0 Journal Article %T Antipsychotic Drug Treatment for Patients with Schizophrenia: Theoretical Background, Clinical Considerations and Patient Preferences %A Ren¨¦ Ernst Nielsen %A Jimmi Nielsen %J Clinical Medicine : Therapeutics %D 2009 %I %X The cornerstone in treatment of psychosis is antipsychotic drugs. Treatment options have increased over the years; newer antipsychotic drugs with a proposed increased efficacy regarding negative and cognitive symptoms, but also a shift in side-effects from neurological side-effects to metabolic side-effects have arisen as the new challenge. The basis of successful pharmacological treatment is a fundamental understanding of the mechanisms of action, the desired effects and side-effects of antipsychotic drugs, a good relationship with the patient and a thorough monitoring of the patient before and during treatment. The clinically relevant aspects of antipsychotic drug treatment are reviewed; mechanism of antipsychotic drug action, clinical considerations in treatment, switching antipsychotic drugs, polypharmacy, safety and patient preference. %K schizophrenia %K treatment %K antipsychotic %K atypical %K interaction %U http://www.la-press.com/antipsychotic-drug-treatment-for-patients-with-schizophrenia-theoretic-a1599