%0 Journal Article %T Extremely low-volume, high-intensity interval training improves exercise capacity and increases mitochondrial protein content in human skeletal muscle %A Jasmin K. Ma %A Trisha D. Scribbans %A Brittany A. Edgett %A J. Colin Boyd %A Craig A. Simpson %A Jonathan P. Little %A Brendon J. Gurd %J Open Journal of Molecular and Integrative Physiology %P 202-210 %@ 2162-2167 %D 2013 %I Scientific Research Publishing %R 10.4236/ojmip.2013.34027 %X

Purpose: The purpose of the present study was to evaluate whole-muscle content of several proteins involved in the regulation of skeletal muscle mitochondrial protein content and anaerobic capacity following 4 weeks of extremely low-volume high-intensity interval training (HIT). Methods: Young, healthy, recreationally active adult males (n = 8) trained 4 times a week for 4 weeks on a cycle ergometer. Each session involved 4 min of total exercise comprised of eight 20 s intervals at ~170% of peak aerobic power separated by 10 s rest. Muscle biopsies were taken prior to (pre) and ~72 hrs post-training (post). Par- ticipants completed an incremental peak oxygen up- take (VO₂peak) test and a Wingate test pre-, mid-, and post-training. Results: VO₂peak was elevated (p < 0.05) at mid- (p < 0.05) and post-training (pre: 40.5 ㊣ 3.8 ml﹞kg^-1﹞min^-1, mid: 43.4 ㊣ 2.5 ml﹞kg^-1﹞min^-1, post-: 47.2 ㊣ 2.9 ml﹞kg^-1﹞min^-1). %K PGC-1汐 %K Mitochondrial Biogenesis %K High-Intensity Interval Training %K SIRT1 %K Aerobic Fitness %U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=39842