%0 Journal Article %T Antenna Modeling and Reconstruction Accuracy of Time Domain-Based Image Reconstruction in Microwave Tomography %A Andreas Fhager %A Shantanu K. Padhi %A Mikael Persson %A John Howard %J International Journal of Biomedical Imaging %D 2013 %I Hindawi Publishing Corporation %R 10.1155/2013/343180 %X Nonlinear microwave imaging heavily relies on an accurate numerical electromagnetic model of the antenna system. The model is used to simulate scattering data that is compared to its measured counterpart in order to reconstruct the image. In this paper an antenna system immersed in water is used to image different canonical objects in order to investigate the implication of modeling errors on the final reconstruction using a time domain-based iterative inverse reconstruction algorithm and three-dimensional FDTD modeling. With the test objects immersed in a background of air and tap water, respectively, we have studied the impact of antenna modeling errors, errors in the modeling of the background media, and made a comparison with a two-dimensional version of the algorithm. In conclusion even small modeling errors in the antennas can significantly alter the reconstructed image. Since the image reconstruction procedure is highly nonlinear general conclusions are very difficult to make. In our case it means that with the antenna system immersed in water and using our present FDTD-based electromagnetic model the imaging results are improved if refraining from modeling the water-wall-air interface and instead just use a homogeneous background of water in the model. 1. Introduction Microwave imaging has received significant attention in the research community during the last couple of decades as a modality that potentially could improve the diagnostics of, for example, breast cancer tumors. Recent progress in the field has been reviewed in [1] and [2]. Today the research has come to the stage where early clinical trials have been and are being performed, [3¨C6]. The results from the clinical work are promising, but further development of the measurement systems as well as of the image reconstruction algorithms remains before the technique can be considered for daily clinical practice. When performing microwave tomography the aim is to quantitatively reconstruct the dielectric parameters in the region under test. This involves solving a computationally challenging nonlinear and ill-posed optimization problem. The image reconstruction algorithm utilizes measured data that are compared against a corresponding numerical simulation of the system, and the dielectric profile is iteratively updated based on the difference between the simulation and the measurement. Even though this comparison requires a realistic numerical model for the best accuracy, most of the published works have used 2D models together with a calibration procedure to enable the comparison with %U http://www.hindawi.com/journals/ijbi/2013/343180/