%0 Journal Article
%T Pregnancy Outcome of Multiparous Women Aged over 40 Years
%A Seda Ates
%A Gonca Batmaz
%A Osman Sevket
%A Taner Molla
%A Cem Dane
%A Banu Dane
%J International Journal of Reproductive Medicine
%D 2013
%I Hindawi Publishing Corporation
%R 10.1155/2013/287519
%X Objective. The aim of this study was to evaluate the effect of maternal age on prenatal and obstetric outcome in multiparaous women. Materials and Methods. A retrospective case control study was conducted, including women aged 40 years and over (study group, ) who delivered at 20 weekĄ¯s gestation or beyond and women aged 20¨C29 years (control group, ). Results. The mean age of women in the study group was years versus years in the control group. Advanced maternal age was associated with a significantly higher rate of hypertension, diabetes mellitus, fetal complication, and 5-minute Apgar scores <7 ( ). Caeserean section rate, incidence of placental abruption, preterm delivery, and neonatal intensive care unit admission were more common in the older group, but the differences were not statistically significant. Conclusions. Advanced maternal age is related to maternal and neonatal complications. 1. Introduction Many women increasingly delay pregnancy and childbirth into their fourth decade of life because of different reasons, such as delay in marriage, educational and professional reasons [1]. Some of them experience pregnancy unwillingly because of inappropriate use of contraceptive methods [2]. Advanced maternal age has been regarded as a risk factor for complications in pregnancy. The association between advanced maternal age and increased risk of chromosomal abnormalities and spontaneous abortion has been well documented in studies [3, 4]. There are different publications in the literature on pregnancy outcomes of women aged 40 years or older. Some authors have reported that advanced maternal age has been associated with preterm delivery, low birth weight, perinatal mortality, and higher frequency of cesarean section [5, 6]. But others have reported no obvious difference in the perinatal outcomes [7], obstetric outcomes [8], birth weight, Apgar score, and admission to neonatal intensive care unit [9] between younger and older mothers. A systematic review stated that advanced aged mothers have an increased risk of stillbirth. The mechanism of the increase in stillbirth risk with advanced maternal age is uncertain [10]. The aim of this study was to determine the effect of maternal age on obstetric and perinatal outcome in multiparous women aged at least 40 year old with multiparous women aged 20¨C29 years. 2. Materials and Methods This is a retrospective study for women delivered at gestational ages of 20 weeks in Bezmialem Vakif University and Haseki Education and Research Hospital between October 2010 and December 2011. We reviewed the obstetric
%U http://www.hindawi.com/journals/ijrmed/2013/287519/