%0 Journal Article
%T Maternofoetal Complications and Their Association with Proteinuria in a Tertiary Care Hospital of a Developing Country
%A Archana Kumari
%A Avinash Chakrawarty
%A Abha Singh
%A Ritu Singh
%J Journal of Pregnancy
%D 2014
%I Hindawi Publishing Corporation
%R 10.1155/2014/431837
%X Objective. To investigate association between maternofoetal complications and the amount of proteinuria measured by spot urine protein creatinine ratio in patients with preeclampsia. Methods. 200 consecutive patients with preeclampsia were recruited in the study. The complications like first episode of severe hypertension, renal insufficiency, raised level of aspartate transaminase, signs of neurological involvement, thrombocytopenia, eclampsia, and need to shift in intensive care units were studied. The maternal outcome was studied in terms of type of labour, outcome of pregnancy, mode of delivery, indication of cesarean section, and maternal mortality. The foetal complications and outcome parameters were birth weight, Apgar score at the time of birth and at five minutes, need of high dependency unit care, and perinatal mortality. Result. The frequency of various maternal and foetal complications was between 14每53% and 22每92%, respectively. Maternal mortality was 3%, whereas perinatal mortality was 23%. Statistically significant association was found between the frequencies of various complications in mother and newborn and spot UPCR. Conclusion. The rate of various maternofoetal complications in preeclampsia is higher in developing countries than in developed world. Maternofoetal complications and outcome correlate with maternal spot UPCR. 1. Introduction Preeclampsia is a major health problem in maternal health with the prevalence ranging from 1.8% to 16.7% in developing countries [1]. This multisystem disorder affects millions of women worldwide and is recognized as an important direct cause of maternal and foetal morbidity and mortality [2]. The course, prognosis, and outcome of this disease are quite heterogeneous and there exists great difference in the morbidity and outcome in the patients of developing and developed world. While there is lack of data from developing countries, studies from the developed world have reported complications in less than 10% [3每5]. Recently, great interest has been shown by investigators all around the world to find out predictors/markers that can predict the maternofoetal outcome in patients with preeclampsia [6每8]. A couple of studies have also been done to find out association between the amount of proteinuria and maternofoetal outcome in patients with preeclampsia but the results have been variable [9每11]. At our centre, we have found relatively high prevalence of maternofoetal complications in patients with preeclampsia. This study was carried out in patients with preeclampsia to estimate the prevalence of
%U http://www.hindawi.com/journals/jp/2014/431837/