%0 Journal Article
%T Effect of Aerobic Training on Cognitive Function and Arterial Stiffness in Sedentary Young Adults: A Pilot Randomized Controlled Trial
%A Samuel Asamoah
%A Jason Siegler
%A Dennis Chang
%A Andrew Scholey
%A Alan Yeung
%A Birinder S. Cheema
%J Physiology Journal
%D 2013
%I Hindawi Publishing Corporation
%R 10.1155/2013/847325
%X This study measured cognitive and vascular responses to aerobic training in sedentary young adults. Ten adults (6 women, 4 men; 18¨C29 years) were randomly assigned to an experimental or no-treatment control group. The experimental group engaged in a 6-week intervention, performed on exercise cycle and treadmill, 3x/week, 50£¿min/session; intensity was increased over time. Outcome measures included arterial stiffness (augmentation index, AIx, and pulse pressure), cardiorespiratory fitness ( ), and cognitive function (attention, processing speed, working memory, episodic memory, and executive function). Participants randomized to aerobic training improved processing speed versus control ( , ES£¿=£¿0.55). However, no group ¡Á time effects were noted in other domains of cognitive function. AIx was reduced by approximately 16% from before to after intervention in the experimental group; however, the improvement was not statistically significant versus control ( , ES£¿=£¿0.22). Pulse pressure did not change between groups over time ( , ES£¿=£¿0.0). increased by approximately 10% in the experimental group; however, the change was not significant between groups over time ( , ES£¿=£¿0.27). Vascular and cognitive adaptations to aerobic training may move in parallel. Robust trials simultaneously investigating a broad spectrum of aerobic training interventions and vascular and cognitive outcomes are warranted. 1. Introduction Aging is associated with neurocognitive decline, which can lead to mild cognitive impairment (MCI) and dementia such as Alzheimer¡¯s disease [1]. Epidemiological data have shown that higher levels of physical activity [2¨C4] and fitness [5¨C8] are associated with better cognitive function and protect against cognitive decline [9]. Moreover, a recent meta-analysis of 29 randomized controlled trials involving healthy and chronically diseased adults of all ages, including individuals with MCI, concluded that aerobic training for more than one month can significantly improve measures of cognitive function, including attention, processing speed, memory, and executive function (i.e., cognitive flexibility) [10]. Such findings have led to a general consensus that exercise can enhance and/or maintain cognitive vitality throughout the lifespan [11]. Accordingly, exercise interventions to prevent cognitive decline should be initiated or maintained in early adulthood when participation in strenuous physical activities is often markedly reduced [12]. Measures of arterial stiffness (e.g., augmentation index, pulse pressure) increase as a consequence of aging and
%U http://www.hindawi.com/journals/physiology/2013/847325/