%0 Journal Article
%T Predictors' Factors of Nutritional Status of Male Chronic Obstructive Pulmonary Disease Patients
%A Elham Pirabbasi
%A Mahin Najafiyan
%A Maria Cheraghi
%A Suzana Shahar
%A Zahara Abdul Manaf
%A Norfadilah Rajab
%A Roslina Abdul Manap
%J ISRN Nursing
%D 2012
%R 10.5402/2012/782626
%X Chronic obstructive pulmonary disease (COPD) is a systemic disease that leads to weight loss and muscle dysfunction resulting in an increase in mortality. This study aimed to determine the prevalence rate of malnutrition and nutritional status and also factors associated with nutritional status. A total of 149 subjects were involved in the cross-sectional study. The study was conducted at two medical centers in Kuala Lumpur, Malaysia. The results of the study showed that malnutrition was more prevalent (52.4%) in the subjects with severe stages of COPD as compared to mild and moderate COPD stages (26.2%) ( ). Fat-free mass depletion as assessed using fat-free mass index (FFMI) affected 41.9% of the subjects. Plasma vitamin A, peak expiratory flow (PEF), and handgrip were the predictors for body mass index (BMI) ( , ). Plasma vitamin A and force expiratory volume in one second (FEV1) were the predictors of FFMI ( , ). BMI was the predictor of respiratory factors, that is, FEV1% predicted ( , ). It can be concluded that there is a need to identify malnourished COPD patients for an appropriate nutrition intervention. 1. Introduction Chronic obstructive pulmonary disease (COPD) is a treatable and preventable disease. It is characterized by an airflow limitation which is not fully reversible [1]. COPD affects the lungs and produces significant systemic consequences such as weight loss and muscle dysfunction [2]. Weight loss and depletion of fat-free mass (FFM) may be observed in stable COPD patients, irrespective of the degree of airflow limitation. Weight loss and underweight are associated with an increased mortality risk. Weight loss and particularly muscle wasting contributes significantly to morbidity, disability, and handicap in COPD patients [1]. Skeletal muscle wasting is commonly present in patients with COPD and may also be present in patients with a stable weight [1]. Weight loss and loss of fat mass are primarily the result of a negative balance between dietary intake and energy expenditure, while muscle wasting is a consequence of an impaired balance between protein synthesis and protein breakdown. In advanced stages of COPD both energy balance and protein balance are disturbed. Therefore, nutritional therapy may only be effective if combined with exercise or other anabolic stimuli. Nutritional intervention should focus more on prevention and early treatment of weight loss to preserve energy balance [1]. Weight loss and being underweight are associated with decreased diffusing capacity and are observed more frequently in emphysematous patients
%U http://www.hindawi.com/journals/isrn.nursing/2012/782626/