%0 Journal Article
%T Can Zoledronic Acid be Beneficial for Promoting Tumor Response in Breast Cancer Patients Treated with Neoadjuvant Chemotherapy?
%A Ayoub Charehbili
%A Duveken B. Y. Fontein
%A Judith R. Kroep
%A Gerrit-Jan Liefers
%A Johannes W. R. Nortier
%A Cornelis J. H. van de Velde
%J Journal of Clinical Medicine
%D 2013
%I MDPI AG
%R 10.3390/jcm2040188
%X The antitumor effect of bisphosphonates (BPs) is under increasing scrutiny. Preclinical and clinical evidence has shown that BPs might sensitize breast tumors to chemotherapy. Here, we present a review of current preclinical and clinical evidence for antitumor effects of BPs, and evaluate how BPs might play a role in neoadjuvant treatment of women with breast cancer.
%K bisphosphonates
%K zoledronic acid
%K chemotherapy
%K neoadjuvant
%K postmenopausal
%U http://www.mdpi.com/2077-0383/2/4/188