%0 Journal Article
%T Synthesis and X-Ray Structure of Important Anticancer Nucleosides Intermediate  (2<i>R</i>,3<i>S</i>,4<i>S</i>,5<i>R</i>)-2-(acetoxymethyl)-5- (3-bromo-5-(methoxycarbonyl)- 1<i>H</i>-1,2,4-triazol-1-yl)tetrahydrofuran- 3,4-diyl Diacetate
%A Yang Liu
%A Guanghui Tian
%A Hongguang Ge
%A Xiaoyan Cao
%A Daihua Hu
%A Dehua Zhang
%J Journal of Crystallization Process and Technology
%P 140-144
%@ 2161-7686
%D 2014
%I Scientific Research Publishing
%R 10.4236/jcpt.2014.43018
%X <div style=\"text-align:justify;\">
	<span \"=\"\" style=\"font-size:10pt;\"><span style=\"font-family:Verdana;font-size:12px;\">An
important anticancer nucleosides intermediate (<span style=\"white-space:nowrap;\">2<i>R</i>,3<i>S</i>,4<i>S</i>,5<i>R</i></span></span><i><span style=\"font-family:Verdana;font-size:12px;\"></span></i><span style=\"font-family:Verdana;font-size:12px;\">)-2-(acetoxymethyl)-5-(3-bromo-5-(methoxycar-bonyl)-1<i></i></span><i><span style=\"font-family:Verdana;font-size:12px;\">H</span></i></span><span style=\"font-size:12px;line-height:1.5;font-family:Verdana;\">-1,2,4-triazol-1-yl)tetrahydrofuran-3,4-diyl
diacetate was synthesized by directly coupling the bromotriazole with the
protected ribose sugar, and have given the corresponding product in moderate
yield. Its structure and conformation were confirmed by single crystal X-ray
diffraction.</span> 
</div>
%K Anticancer Nucleosides
%K Intermediate
%K Triazole Nucleosides
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=47515