%0 Journal Article
%T The Role of <sup>18</sup>F-FDG-PET/CT in the Management of Patients with High-Risk Breast Cancer: Case Series and Guideline Comparison
%A Ben F. Bulten
%A Marie J. de Haas
%A Haiko J. Bloemendal
%A Adriaan J. van Overbeeke
%A Jan Paul Esser
%A Henk J. Baarslag
%A Lioe-Fee de Geus-Oei
%A C. J. Rodenburg
%A John M. H. de Klerk
%J Advances in Molecular Imaging
%P 35-41
%@ 2161-6752
%D 2014
%I Scientific Research Publishing
%R 10.4236/ami.2014.43005
%X <div style=\"text-align:justify;\">
	<span style=\"font-family:Verdana;font-size:12px;\">Objectives: In grade III-IV breast cancer, dissemination of disease
needs to be assessed. Until now this was done by conventional imaging (liver ultrasonography,
chest X-ray and bone scintigraphy), but evidence favoring the use of FDG-PET/CT
is accumulating. Methods: Patients with high-risk breast cancer, who had
received conventional imaging and FDG-PET/CT, were included. Patients were
staged and assigned a treatment after 1) conventional imaging and 2)
FDG-PET/CT, both by a multidisciplinary oncology team. Equivocal FDG-PET/CT
findings were histologically confirmed. Results: 16 patients were included
(mean age 59 years). TNM-stage changed in 5 patients (31%) after FDG-PET/CT. In
3 patients (19%) un</span><span style=\"font-family:Verdana;font-size:12px;\">known distant metastases
were detected b</span><span style=\"font-family:Verdana;font-size:12px;\">y FDG-PET/CT. An adjustment of treatment took place in 4
patients (25%). Conclusions: Our case series emphasizes the role of
FDG-PET/CT in the staging of high-risk breast carcinoma, especially in the
assessment of distant metastases. We suggest replacing conventional imaging
with FDG-PET/CT.</span>
</div>
%K Breast Cancer
%K FDG-PET/CT
%K Staging
%K Dissemination
%K Guidelines
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=47607