%0 Journal Article
%T Excessive Sensitivity to Uncertain Visual Input in L-DOPA-Induced Dyskinesias in Parkinson¡¯s Disease: Further Implications for Cerebellar Involvement
%A James K. R. Stevenson
%A Chonho Lee
%A Kristina Aseeva
%A Meeko M. K. Oishi
%A Martin J. McKeown
%J Frontiers in Neurology
%D 2014
%I Frontiers Media
%R 10.3389/fneur.2014.00008
%X When faced with visual uncertainty during motor performance, humans rely more on predictive forward models and proprioception and attribute lesser importance to the ambiguous visual feedback. Though disrupted predictive control is typical of patients with cerebellar disease, sensorimotor deficits associated with the involuntary and often unconscious nature of l-DOPA-induced dyskinesias in Parkinson¡¯s disease (PD) suggests dyskinetic subjects may also demonstrate impaired predictive motor control.
%K l-DOPA-induced dyskinesias
%K Parkinson¡¯s disease
%K dynamical system models
%K visually guided tracking
%K visual uncertainty
%U http://www.frontiersin.org/Journal/10.3389/fneur.2014.00008/abstract