%0 Journal Article
%T A prospective assessment of the effect of aminophylline therapy on urine output and inflammation in critically ill children
%A Robert F. Tamburro
%A Neal J. Thomas
%A Gary D. Ceneviva
%A Michael D. Dettorre
%A Steven E. Lucking
%J Frontiers in Pediatrics
%D 2014
%I Frontiers Media
%R 10.3389/fped.2014.00059
%X Background: Aminophylline, an established bronchodilator, is also purported to be an effective diuretic and anti-inflammatory agent. However, the data to support these contentions are scant. We conducted a prospective, open-label, single arm, single center study to assess the hypothesis that aminophylline increases urine output and decreases inflammation in critically ill children.
%K aminophylline
%K respiratory function
%K inflammation
%K pediatrics
%K phosphodiesterase inhibition
%K adenosine receptor blockade
%K acute kidney injury
%U http://www.frontiersin.org/Journal/10.3389/fped.2014.00059/abstract