%0 Journal Article
%T 尿素通道蛋白B的转运特性
Transport Characteristics of Urea Transporter-B
%A 钟丹丹
%A 杨宝学
%J Journal of Physiology Studies
%P 1-4
%@ 2330-1600
%D 2014
%I Hans Publishing
%R 10.12677/JPS.2014.21001
%X
尿素通道蛋白B(urea transporters B, UT-B)主要表达在红细胞和一些上皮及内皮细胞膜,介导尿素的跨膜转运。近年来研究发现UT-B亦参与其他物质的转运,如水、NH<sub>3</sub>和尿素类似物等,提示UT-B还可以作为水和气体通道。本文主要阐述UT-B对这些物质的转运特性,并探究其可能的生理学意义。
Urea transporter UT-B is highly expressed in the membrane of erythrocytes and some epithelial and endothelial cells, in which UT-B facilitates urea transport. Recently, studies find that water, ammonia and urea analogues can also be transported by UT-B. This review mainly focuses on the transport characteristics of UT-B, and the possible physiological significance will be discussed as well.
%K 尿素通道蛋白B;尿素;尿素类似物;NH3;水
UT-B
%K Urea
%K Urea Analogues
%K Ammonia
%K Water
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=13380