%0 Journal Article %T 尿素通道蛋白B的转运特性
Transport Characteristics of Urea Transporter-B %A 钟丹丹 %A 杨宝学 %J Journal of Physiology Studies %P 1-4 %@ 2330-1600 %D 2014 %I Hans Publishing %R 10.12677/JPS.2014.21001 %X
尿素通道蛋白B(urea transporters B, UT-B)主要表达在红细胞和一些上皮及内皮细胞膜,介导尿素的跨膜转运。近年来研究发现UT-B亦参与其他物质的转运,如水、NH<sub>3</sub>和尿素类似物等,提示UT-B还可以作为水和气体通道。本文主要阐述UT-B对这些物质的转运特性,并探究其可能的生理学意义
Urea transporter UT-B is highly expressed in the membrane of erythrocytes and some epithelial and endothelial cells, in which UT-B facilitates urea transport. Recently, studies find that water, ammonia and urea analogues can also be transported by UT-B. This review mainly focuses on the transport characteristics of UT-B, and the possible physiological significance will be discussed as well.
%K 尿素通道蛋白B;尿素;尿素类似物;NH3;水
UT-B %K Urea %K Urea Analogues %K Ammonia %K Water %U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=13380