%0 Journal Article
%T 外周血可溶性CD28含量与Graves疾病的相关性研究<br>Correlation Analysis of Concentration of Plasma Soluble CD28 and Graves Disease
%A 孙中文
%A 陶鸿
%A 孙静
%A 黄静芳
%A 易丽娴
%A 陈蕾
%J Immunology Studies
%P 11-16
%@ 2330-1678
%D 2014
%I Hans Publishing
%R 10.12677/IS.2014.22003
%X <div style=\"text-align:justify;\">
	<span style=\"line-height:1.5;\">目的：探讨</span><span style=\"line-height:1.5;\">Graves</span><span style=\"line-height:1.5;\">病患者外周血中可溶性</span><span style=\"line-height:1.5;\">CD28</span><span style=\"line-height:1.5;\">分子浓度与</span><span style=\"line-height:1.5;\">FT3</span><span style=\"line-height:1.5;\">、</span><span style=\"line-height:1.5;\">FT4</span><span style=\"line-height:1.5;\">、</span><span style=\"line-height:1.5;\">sTSH</span><span style=\"line-height:1.5;\">和</span><span style=\"line-height:1.5;\">TRAb</span><span style=\"line-height:1.5;\">等实验室参数的相关性，以分析外周血可溶性</span><span style=\"line-height:1.5;\">CD28</span><span style=\"line-height:1.5;\">分子含量测定对</span><span style=\"line-height:1.5;\">Graves</span><span style=\"line-height:1.5;\">病的临床辅助诊断价值。方法：采用双单抗夹心酶联检测法分析</span><span style=\"line-height:1.5;\">Graves</span><span style=\"line-height:1.5;\">病患者血液中可溶性</span><span style=\"line-height:1.5;\">CD28</span><span style=\"line-height:1.5;\">分子的含量；化学发光免疫法检测血液中甲状腺功能指标</span><span style=\"line-height:1.5;\">FT3</span><span style=\"line-height:1.5;\">、</span><span style=\"line-height:1.5;\">FT4</span><span style=\"line-height:1.5;\">、</span><span style=\"line-height:1.5;\">sTSH</span><span style=\"line-height:1.5;\">的浓度；</span><span style=\"line-height:1.5;\">ELISA</span><span style=\"line-height:1.5;\">法测定血液中</span><span style=\"line-height:1.5;\">TRAb</span><span style=\"line-height:1.5;\">的含量。结果：</span><span style=\"line-height:1.5;\">Graves</span><span style=\"line-height:1.5;\">病人血液中可溶性</span><span style=\"line-height:1.5;\">CD28</span><span style=\"line-height:1.5;\">分子含量</span><span style=\"line-height:1.5;\">(3.42 ± 0.74 ng/ml)</span><span style=\"line-height:1.5;\">明显高于健康对照组</span><span style=\"line-height:1.5;\">(0.83 ± 0.29 ng/ml) (</span><span style=\"line-height:1.5;\">p </span><span style=\"line-height:1.5;\">&lt; 0.01)</span><span style=\"line-height:1.5;\">；患者体内可溶性</span><span style=\"line-height:1.5;\">CD28</span><span style=\"line-height:1.5;\">分子的表达水平与</span><span style=\"line-height:1.5;\">FT3</span><span style=\"line-height:1.5;\">、</span><span style=\"line-height:1.5;\">FT4</span><span style=\"line-height:1.5;\">和</span><span style=\"line-height:1.5;\">TRAb</span><span style=\"line-height:1.5;\">浓度均呈正相关关系，相关系数</span><span style=\"line-height:1.5;\">γ</span><span style=\"line-height:1.5;\">分别为</span><span style=\"line-height:1.5;\">0.786</span><span style=\"line-height:1.5;\">、</span><span style=\"line-height:1.5;\">0</span><span style=\"line-height:1.5;\">.746</span><span
%K Graves病，可溶性CD28分子，相关性<br>Graves’ Disease
%K Soluble CD28
%K Correlation
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=13460