%0 Journal Article
%T 盐酸文拉法辛的合成
Synthesis of Venlafaxine Hydrochloride
%A 朱园园
%A 李婷婷
%A 古双喜
%J Studies in Synthetic Chemistry
%P 1-3
%@ 2332-7960
%D 2013
%I Hans Publishing
%R 10.12677/SSC.2013.11001
%X
以廉价易得的茴香醇为原料,经7步反应以56.7%的总收率合成得到盐酸文拉法辛。该路线简捷高效,反应条件温和,后处理操作简单,适合工业化生产。
Venlafaxine hydrochloride was synthesized via 7-step reactions in the total yield of 56.7% from anisic alcohol. The synthetic route is concise and efficient, and suitable for industrialization due to its mild reaction conditions and simple post-treatment.
%K 盐酸文拉法辛;合成;抗抑郁药;茴香醇