%0 Journal Article %T 盐酸文拉法辛的合成
Synthesis of Venlafaxine Hydrochloride %A 朱园园 %A 李婷婷 %A 古双喜 %J Studies in Synthetic Chemistry %P 1-3 %@ 2332-7960 %D 2013 %I Hans Publishing %R 10.12677/SSC.2013.11001 %X

以廉价易得的茴香醇为原料,经7步反应以56.7%的总收率合成得到盐酸文拉法辛。该路线简捷高效,反应条件温和,后处理操作简单,适合工业化生产。 

Venlafaxine hydrochloride was synthesized via 7-step reactions in the total yield of 56.7% from anisic alcohol. The synthetic route is concise and efficient, and suitable for industrialization due to its mild reaction conditions and simple post-treatment.

 

%K 盐酸文拉法辛;合成;抗抑郁药;茴香醇
Venlafaxine Hydrochloride %K Synthesis %K Antidepressant %K Anisic Alcohol %U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=12453