%0 Journal Article
%T 莫达非尼的合成新方法<br>New Synthesis Way of Modafinil
%A 史云争
%A ZhangXiaohui
%A 周毅
%A 李德鹏
%J Studies in Synthetic Chemistry
%P 51-55
%@ 2332-7960
%D 2014
%I Hans Publishing
%R 10.12677/SSC.2014.23006
%X <div style=\"text-align:justify;\">
	<span style=\"line-height:1.5;\">莫达非尼是一种新型的中枢神经精神兴奋药物，毒副作用小。本文提出了中枢神经兴奋药物莫达非尼合成的新方法，改进了莫达非尼合成路线，优化了合成工艺条件，大大地缩短了反应时间，反应条件温和，合成操作简便。用IR、MS、1H-NMR表征了主要产物结构。&lt;br/&gt;Modafinil is a novel central stimulant drug and relatively small in side effects. The new synthetic route of Modafinil was designed in this paper. Improved synthetic route of modafinil and optimized synthetic conditions were investigated. The reaction time was greatly shortened, the reactions condition was mild and the operation of synthesis was simple. Key products were characterizated by IR, MS and 1H NMR.</span>
</div>
%K 莫达非尼，二苯甲硫代乙酰胺，硫脲，合成<br>Modafinil
%K 2-Benzhydrylsulfanylacetamide
%K Thiourea
%K Synthesis
%U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=14248