%0 Journal Article
%T Quercetin as a Protease (¨˘-Chymotrypsin) Inhibitor
%A GB Bajracharya
%A DB Thapa
%J Nepal Journal of Science and Technology
%P 91-96
%D 2013
%R 10.3126/njst.v14i2.10420
%X Quercetin, isolated from the skin of red onion bulb, was methylated to afford quercetin 3,3’,4’,7-tetramethyl ether in 83.3% yield. Quercetin has displayed α-chymotrypsin inhibitory effect (IC 50 = 88.9 ± 2.5 ìg/ml), DPPH free radical scavenging activity (IC 50 = 14.87 ìg/ml) and ferric reducing power (EC1 = 112.94 ìM/l equivalent to 1 mM/l FeSO 4 .7H 2 O), whereas no enhancement of these biological activities was observed using its tetramethyl ether derivative. DOI: http://dx.doi.org/10.3126/njst.v14i2.10420   Nepal Journal of Science and Technology Vol. 14, No. 2 (2013) 91-96
%K Allium cepa
%K ¨˘-chymotrypsin
%K DPPH assay
%K FRAP assay
%K quercetin 3
%K 3ĄŻ
%K 4ĄŻ
%K 7-tetramethyl ether
%U http://www.nepjol.info/index.php/NJST/article/view/10420