%0 Journal Article
%T Biliary Adenofibroma with Carcinoma In Situ: A Rare Case Report
%A N. Thao T. Nguyen
%A Theresa R. Harring
%A Laurie Holley
%A John A. Goss
%A Christine A. O'Mahony
%J Case Reports in Hepatology
%D 2012
%I Hindawi Publishing Corporation
%R 10.1155/2012/793963
%X This case report exhibits a rare biliary tumor within the liver of a 53-year-old Caucasian woman. This exophytic, multicystic, 6.5 กม 5.0 cm mass was composed of complex tubulocystic structures lined by nonmucin-secreting, biliary epithelium embedded in fibrous stroma, consistent with biliary adenofibroma. This is the seventh case described in the literature. Multiple foci of high-grade dysplasia/carcinoma in situ were found with a microscopic focus of invasive carcinoma in review of the pathology, making this only the second case reporting malignant transformation. It is presented to illustrate the premalignant potential in a biliary epithelial tumor currently categorized as benign.
%U http://www.hindawi.com/crim/hepatology/2012/793963/