%0 Journal Article
%T Seasonality and Sleep: A Clinical Study on Euthymic Mood Disorder Patients
%A Chiara Brambilla
%A Chiara Gavinelli
%A Dario Delmonte
%A Mara Cigala Fulgosi
%A Barbara Barbini
%A Cristina Colombo
%A Enrico Smeraldi
%J Depression Research and Treatment
%D 2012
%I Hindawi Publishing Corporation
%R 10.1155/2012/978962
%X Background. Research on mood disorders has progressively focused on the study of seasons and on the mood in association with them during depressive or manic episodes yet few studies have focused on the seasonal fluctuation that characterizes the patient's clinical course both during an illness episode and during euthymic periods. Methods. 113 euthymic outpatients 46 affected by major recurrent depression and 67 affected by bipolar disorder were recruited. We evaluated the impact of clinical ¡°rhythmical¡± factors: seasonality, sleep disturbance, and chronotype. Patients completed the SPAQ questionnaire, the MEQ questionnaire, and the medical outcomes study (MOS) sleep scale. We used t-test analyses to compare differences of clinical ¡°rhythmical¡± and sociodemographic variables and of differences in the assessment scales among the diagnostic groups. Results. Patients reporting a family history for mood disorders have higher fluctuations throughout seasons. Sleep disturbance is more problematic in unipolars when compared to bipolars. Conclusions. Sleep, light, and seasonality seem to be three interconnected features that lie at the basis of chronobiology that, when altered, have an important effect both on the psychopathology and on the treatment of mood disorders. 1. Introduction The degree to which seasonal changes affect mood is known as seasonality. The periodical pattern of recurrence is a biological feature of mood disorders, and the recovery from the first episode of illness is followed by a subsequent recurrence in about 90% of affected patients during their lifetime [1]. In addition, the occurrence of diurnal variations in mood and of distressful and pervasive disruption in sleep suggests a primary disturbance of biological rhythms for mood disorders [2]. The typical pattern of recurrence of mood disorder follows interindividual rules, since each patient presents their own specific pattern with a few episodes during their life, or more than four episodes each year (rapid cycler). Some authors have stressed the concept of seasonality, as many patients show critical months of the year when they tend to have a new recurrence independent of polarity [3]. The recurrence pattern is also affected by external factors, such as exposition to light which appears to have an antidepressant effect both on its own and when associated to acute pharmacological treatments, which shorten the subsequent cycle of illness [4] and maintenance treatments, which are expected to decrease the episode rates. Mood stabilizers, the first choice of treatment for bipolar disorder,
%U http://www.hindawi.com/journals/drt/2012/978962/