%0 Journal Article
%T Propyl Gallate Plays a Nephroprotective Role in Early Stage of Diabetic Nephropathy Associated with Suppression of Glomerular Endothelial Cell Proliferation and Angiogenesis
%A Shaojiang Tian
%A Junming Tang
%A Huihui Liu
%A Liping Wang
%A Jianming Shen
%A Junfeng Li
%A Yanjie Gan
%J Experimental Diabetes Research
%D 2012
%I Hindawi Publishing Corporation
%R 10.1155/2012/209567
%X There is growing evidence suggesting that glomerular endothelial cell proliferation and angiogenesis may be responsible for the pathophysiological events in the early stage of diabetic nephropathy. This study was designed to investigate the factors related to glomerular endothelial cell proliferation and glomerular angiogenesis and assess the effect of propyl gallate on preventing these disorders in diabetic rats. We found that glomerular hypertrophy, glomerular mesangial matrix expansion, and albuminuria were significantly increased in DN rats. CD31
%U http://www.hindawi.com/journals/edr/2012/209567/