%0 Journal Article %T 微波辐射有机药物合成研究进展
Organic Drug Synthesis Assisted with Microwave Irradiation %A 韩谢 %A 邵开元 %A 胡文祥 %J Journal of Microwave Chemistry %P 15-21 %@ 2576-1129 %D 2017 %I Hans Publishing %R 10.12677/mc.2017.11004 %X
本文综述了近年微波辐射技术应用于加速有机药物合成中的部分主要反应类型,包括酰化反应、环合反应、不对称烷基化、消除反应、重排反应、还原反应等。相比传统经典有机合成反应,微波辐射具有缩短反应时间,提高产率,减少副产物等优势。因此,近年来发展十分迅速。
In this paper, the main types of organic drug synthesis assisted with microwave irradiation in re-cent years have been reviewed, including acylation, cyclization, asymmetric alkylation, elimination, rearrangement and reduction reaction. Compared with the traditional method, microwave assisted synthesis can greatly improve the yield and shorten the reaction time. Therefore, the development of microwave assisted synthesis in recent years become very rapid.
%K 有机合成,药物合成,微波辐射
Organic Synthesis %K Drug Synthesis %K Microwave Irradiation %U http://www.hanspub.org/journal/PaperInformation.aspx?PaperID=21791