目的：系统评价人文关怀对ICU综合征发生率的影响。方法：用计算机检索中国期刊全文数据库(CNKI)、中国生物医学文献数据库(CBM)、维普期刊资源整合服务平台(VIP)、万方数字化期刊全文数据库中关于人文关怀对ICU综合征影响的随机对照研究，采用Review Manager 5.3软件对文献进行Meta分析。结果：经筛选后共纳入15个随机对照研究，共1278例患者。Meta分析结果证实，人文关怀可以减少ICU综合征发生率，优于常规护理方法，合并效应均有统计学意义。其中ICU综合征发生率：[(P = 1.00; I2 = 0%)]，采用固定效应模型，[OR = 0.32, 95% CI (0.24, 0.43), Z = 7.51, P < 0.00001]；焦虑评分：[(P = 0.86; I2 = 0%)]，采用固定效应模型，[WMD = ？7.64, 95% CI (？8.77, ？6.50), P < 0.00001]；抑郁评分：[(P = 0.001; I2 = 81%)]，采用随机效应模型，[WMD = ？7.81, 95% CI (？10.01, ？5.61), P < 0.00001]；ICU患者满意度：[(P = 0.71; I2 = 0%)]，采用固定效应模型，[OR = 5.49, 95% CI (2.57, 11.73), Z = 4.39, P < 0.00001]；结论：采用人文关怀对ICU患者进行护理，可以减少ICU综合征的发生，可以减轻患者焦虑和抑郁的程度，提高患者的满意度，明显优于常规护理方法。
Objective: To systematically evaluate the influence of humanistic care on the incidence of ICU syn-drome. Methods: Randomized controlled studies on the influence of humanistic care on ICU syn-drome were retrieved from Chinese journal full text database (CNKI), Chinese biomedical literature database (CBM), technology journals full text database (VIP) and Wanfang Digital Journal Full-text Database by computer. The literature was analyzed by Review Manager 5.3 software. Results: After screening, 15 randomized controlled trials involving 1278 patients were included. Meta-analysis confirmed that humanistic care could reduce the incidence of ICU syndrome, which was superior to conventional nursing methods, and the combined effect was statistically significant. Incidence of ICU syndrome: [(P = 1.00; I2 = 0%)], using Fixed-effect model, [OR = 0.32, 95% CI (0.24, 0.43), Z = 7.51, P < 0.00001]; Anxiety score: [(P = 0.86; I2 = 0%)], using Fixed-effect model, [WMD = ？7.64, 95% CI (？8.77, ？6.50), P < 0.00001]; Depression score: [(P = 0.001; I2 = 81%)], using Stochastic Effect Model, [WMD = ？7.81, 95% CI (？10.01, ？5.61), P < 0.00001]; Satisfaction of ICU patients: [(P = 0.71; I2 = 0%)], using Fixed-effect model, [OR = 5.49, 95% CI (2.57, 11.73), Z = 4.39, P < 0.00001]. Conclusion: Nursing ICU patients with humanistic care can reduce the occurrence of ICU syndrome, alleviate the degree of anxiety and depression, and improve patient satisfaction, which is obviously superior to conventional nursing methods.