%0 Journal Article
%T Malignant Peripheral Nerve Sheath Tumor of the Thigh Invading the Superficial Femoral Artery, with Necrotic Lung Metastases as Presenting Symptoms
%A Patrick Mailleux
%A Fran£żois Buche
%A Geoffrey Colin
%J Advances in Lung Cancer
%P 24-29
%@ 2169-2726
%D 2020
%I Scientific Research Publishing
%R 10.4236/alc.2020.92003
%X A NF1 (neurofibromatosis 1) patient developed multiple necrotic lung metastases</span><span style=\"font-family:Verdana;\">&nbsp;from a sciatic malignant peripheral nerve sheath tumor (MPNST) invading the superficial femoral artery. The first diagnosis was metastases of a non-small-cell adenocarcinoma because the right calf MPNST was not clinical</span><span style=\"font-family:Verdana;\">ly noticeable ant that the chest/abdomen PET/CT did not include the region of the legs. When the MPNST was diagnosed, new histological analysis on the </span><span style=\"font-family:Verdana;\">metastases changed the diagnosis to that of epithelioid undifferentiated sarcoma.</span><span style=\"font-family:Verdana;\">&nbsp;The article deals with the sometimes-delayed diagnosis in those NF1 patients </span><span style=\"font-family:Verdana;\">with large palpable masses and chronic pain pre-existing the malignant transformat</span><span style=\"font-family:Verdana;\">ion, and discusses the difficulty of the biopsy of necrotic metastases.
%K Necrotic Metastasis
%K Malignant Peripheral Nerve Sheath Tumor
%K NF1
%K Lung Adenocarcinoma
%K &lt
%K sup&gt
%K 18&lt
%K /sup&gt
%K F-FDG PET/CT
%K Unknown Primary Tumor
%U http://www.scirp.org/journal/PaperInformation.aspx?PaperID=99969