%0 Journal Article
%T On-line monitoring human breath acetone during exercise and diet by proton transfer reaction mass spectrometry | Bioanalysis
%A Chaoqun Huang
%A Chengyin Shen
%A Dianlong Ge
%A Hongmei Wang
%A Lei Xia
%A Xue Zou
%A Yan Lu
%A Yannan Chu
%J Bioanalysis
%D 2019
%R https://doi.org/10.4155/bio-2018-0258
%X Aim: This study aims to develop a method for monitoring fat loss by detection of breath acetone. Methods: A new method combining direct breath sampling system and proton transfer reaction MS (PTR-MS) was developed for on-line detection of breath acetone. The breath acetone of 272 volunteers was detected respectively when exercise or diet. Results: Exercises perennially can make the breath acetone increase by 40¨C130%. Dinner fasting for 1 week can make it increase by 140%. Conclusion: Exercise and diet are two useful methods to lose fat. Determination of breath acetone concentration using the direct breath sampling system-proton transfer reaction MS can help design scheme of exercise and diet for losing weight.
%U https://www.future-science.com/doi/10.4155/bio-2018-0258