%0 Journal Article %T Use of preimplantation genetic testing for monogenic defects (PGT-M) for adult-onset conditions: an Ethics Committee opinion - Fertility and Sterility %A Elena Gates %A Elizabeth Ginsburg %A Ethics Committee of the American Society for Reproductive Medicine %A Ginny Ryan %A Jean Benward %A Joseph Davis %A Judith Daar %A Julianne Zweifel %A Laurence McCullough %A Lee Collins %A Leslie Francis %A Lynn Westphal %A Mark Sauer %A Owen Davis %A Richard Paulson %A Richard Reindollar %A Sean Tipton %A Sigal Klipstein %A Susan Gitlin %J Fertility and Sterility %D 2018 %R https://doi.org/10.1016/j.fertnstert.2018.04.003 %X Preimplantation genetic testing for monogenic diseases for adult-onset conditions is ethically permissible for a range of conditions including when the condition is serious and no safe, effective interventions are available. The Committee strongly recommends that a genetic counselor experienced with PGT-M counsel patients considering such procedures. This document replaces the document titled ¡°Use of preimplantation genetic diagnosis for serious adult-onset conditions: a committee opinion,¡± last published in Fertil Steril 2013;100;54-7. %U https://www.fertstert.org/article/S0015-0282(18)30328-5/fulltext