%0 Journal Article %T In Vivo Analysis of a Gain-of-Function Mutation Confirms Unc18/Munc18's Role in Priming %A Leonardo A. Parra %J The Journal of Neurosience %D 2018 %R 10.1523/JNEUROSCI.3068-17.2017 %X Neurotransmitter release at synapses is mediated by the fusion of synaptic vesicles with the plasma membrane. Fusion is mediated by the interaction of three SNARE proteins (soluble NSF-attachment receptor): synaptobrevin in the vesicle membrane and syntaxin and SNAP-25 in the plasma membrane ( %U http://www.jneurosci.org/content/38/5/1055