%0 Journal Article %T DIAGNOSTIC POWER OF GENEXPERT MTB/RIF ASSAY FOR RAPID DIAGNOSIS OF TUBERCULOSIS AND DETECTION OF RIFAMPINCIN RESISTANCE IN SMEAR NEGATIVE SPUTUM SAMPLE OF SUSPECTED CASE OF TUBERCULOSIS IN TERTIARY CARE HOSPITAL, JAMNAGAR, GUJARAT %A GAMIT %A S.C. %A MULLAN %A S. %A SHINGALA %A H.K. %J BioInfo Publication %D 2019 %X Tuberculosis is a widespread, infectious disease caused by various strains of Mycobacteria usually Mycobacterium tuberculosis. Tuberculosis typically attacks the lungs and can also affect other parts of the body. An active TB infected patient¡¯s cough, sneeze, or otherwise transmit through respiratory fluids are the common cause for the TB through the air. This study, which was conducted in tertiary care hospital, Jamnagar. There were 2 sputum samples, one spot supervised and one early morning collected and transported from various centres to TB culture-DST laboratory, Total 448 Smear Negative Sputum (Suspected case of Mycobacterium tuberculosis) samples were received during the study period and proceeded by GeneXpert MTB/RIF Assay. Out of total 448 smear negative sputum samples, in 142 sputum samples Mycobacterium tuberculosis Bacilli (MTB) were detected, Out MTB positive cases 12(8.45%) sputum samples resistant to Rifampicin and 103(72.53%) and 39(27.47%) cases from male and female gender respectively. highest number of MTB positive cases were found in age group of 21-30 years which were 38(26.8%) followed by 31-40 years which were 37(26%). Out total 448 Smear Negative Sputum 74 HIV positive sputum samples, in 18 samples Mycobacterium tuberculosis Bacilli (MTB) were detected. The study revealed the GeneXpert MTB/RIF Assay test offers a potential solution for improving early MTB diagnosis %U https://bioinfopublication.org/viewhtml.php?artid=BIA0004980