%0 Journal Article
%T Thyrotoxic hypokalemic periodic paralysis due to GravesĄŻ disease in 2 adolescents
%A Hae Sang Lee
%A Jin Soon Hwang
%A Jung Gi Roh
%A Kyu Jung Park
%J Archive of "Annals of Pediatric Endocrinology & Metabolism".
%D 2019
%R 10.6065/apem.2019.24.2.133
%X Thyrotoxic periodic paralysis (TPP) is a notable and potentially lethal complication of thyrotoxicosis, and GravesĄŻ disease is the most common cause of TPP. TPP is commonly reported in Asian males between 20¨C40 years of age, but it is rare in children and adolescents. We report 2 Korean adolescents (a 16-year-old male and a 14-year-old female) with episodes of TPP who were previously diagnosed with GravesĄŻ disease. These 2 patients presented with lower leg weakness in the morning after waking up. They were diagnosed with TPP-associated with thyrotoxicosis due to GravesĄŻ disease. After they were initially treated with potassium chloride and antithyroid drugs, muscle paralysis improved and an euthyroid state without muscle paralytic events was maintained during follow-up. Therefore, clinicians should consider TPP when patients have sudden paralysis and thyrotoxic symptoms such as goiter, tachycardia, and hypertension
%K Thyrotoxic periodic paralysis
%K Hypokalemia
%K GravesĄŻ disease
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6603612/