%0 Journal Article
%T Novel Bacillus subtilis Spore-Displayed Tyrosinase Kit for Rapid Detection of Tyrosine in Urine: Pharmaceutical Applications for the Early Diagnosis of Kidney-Related Diseases
%A Afrouzossadat Hosseini Abari
%A Byung Gee Kim
%A Giti Emtiazi
%A Junehyung Kim
%A Maziyar Tayebi
%J Archive of "Advanced Pharmaceutical Bulletin".
%D 2019
%R 10.15171/apb.2019.040
%X Purpose: Simple and cheap diagnostic kit development is one of the important aims of pharmaceutical developers and companies focused on public health improvement. The Bacillus subtilis spore surface-display technique is a genetic engineering method that is used to develop new-generation diagnostic kits applicable for the early detection of various types of diseases. In this study, we developed a novel simple, rapid, and inexpensive diagnostic paper-based kit to detect tyrosine in urine samples of humans and animals that is applicable for home or laboratory use
%K Chronic kidney disease
%K Diabetes
%K Health protection program
%K Pharmaceutical developers
%K Spore-displayed tyrosinase
%K Tyrosine
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664106/