%0 Journal Article
%T Combination of Vildagliptin and Ischemic Postconditioning in Diabetic Hearts as a Working Strategy to Reduce Myocardial Reperfusion Injury by Restoring Mitochondrial Function and Autophagic Activity
%A Alireza Alihemmati
%A Aniseh Javadi
%A Goltaj Bayrami
%A Milad Zadi-Heydarabad
%A Mustafa Mohammadi
%A Pouran Karimi
%A Rana Keyhanmanesh
%A Reza Badalzadeh
%J Archive of "Advanced Pharmaceutical Bulletin".
%D 2018
%R 10.15171/apb.2018.037
%X Purpose: Diabetic hearts are resistant to cardioprotection by ischemic-postconditioning (IPostC). Protection of diabetic hearts and finding related interfering mechanisms would have clinical benefits. This study investigated the combination effects of vildagliptin (Vilda) and IPostC on cardioprotection and the levels of autophagy and mitochondrial function following myocardial ischemia/reperfusion (I/R) injury in type-II diabetic rats
%K Ischemic postconditioning
%K Diabetes
%K Reperfusion injury
%K Autophagy
%K Mitochondrial function
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6046419/