%0 Journal Article
%T ANTITUMOR AND APOPTOTIC EFFECTS OF CUCURBITACIN A IN A-549 LUNG CARCINOMA CELLS IS MEDIATED VIA G2/M CELL CYCLE ARREST AND M-TOR/PI3K/AKT SIGNALLING PATHWAY
%A Dan Shang
%A Hong-ju Liu
%A Juan-juan Xu
%A Wen-dong Wang
%A Xian-zhi Xiong
%A Yan Liu
%A Yuan Su
%J Archive of "African Journal of Traditional, Complementary, and Alternative Medicines".
%D 2017
%R 10.21010/ajtcam.v14i2.9
%X The main aim of this study was to demonstrate the antitumor potential of cucurbitacin A on A-549 NSCLC (non-small cell lung cancer cells). The effects of Cucurbitacin A on apoptotic induction, cell physic, cell cycle failure and m-TOR/PI3K/Akt signalling pathway were also investigated in the present study
%K Non-small cell lung cancer
%K apoptosis
%K cucurbitacin A
%K cell cycle
%K antitumor activity
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5446468/