%0 Journal Article
%T Evaluation of NPP1 as a Novel Biomarker of Coronary Artery Disease: A Pilot Study in Human Beings
%A Afsaneh Mohammadi
%A Amir Hooshang Mohammadpour
%A Atefeh Rezapour
%A Azadeh Zayerzadeh
%A Fatemeh Mashhadi
%A Hamid Reza Mashreghi Moghadam
%A Maryam Moradian
%A Mohammad Afshar
%A Saeed Falahaty
%A Saeed Nazemi
%A Sepideh Afzalnia
%A Sepideh Elyasi
%A Seyed Mohammad Hasan Moallem
%J Archive of "Advanced Pharmaceutical Bulletin".
%D 2018
%R 10.15171/apb.2018.057
%X Purpose: Coronary artery calcification (CAC) is utilized as an important tool for global risk assessment of cardiovascular events in individuals with intermediate risk. Ecto phosphodiesterase/nucleotide phosphohydrolase-1(ENPP1) converts extracellular nucleotides into inorganic pyrophosphate and it is a key regulator of tissue calcification that adjusts calcification in tissues like vascular smooth muscle cells. The main purpose of this clinical study was to find out the correlation between ENPP1 serum concentration and CAC in human for the first time
%K Coronary Artery Calcification
%K ENPP1
%K Biomarker
%K Inorganic pyrophosphate
%K Glycoprotein 1- nucleotides
%U https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6156488/